It is very important to understand that our body does need some biological system to interact with, to experience the therapeutic effects of the cannabis plant and this is called the endocannabinoid system (ECS). The ECS allows us to use CBD for pain, anxiety, depression, etc., and make use of every strain of this cannabis plant.
So many questions arise amongst new users on how does CBD work on our body? How many CBD gummy bears should I eat? To get the benefits of CBD. Hence, all users need to understand what happens in our system. Also, we got these online sites like the Just CBD store who can help you with the servings of CBD required by each individual.
ECS is very important to regulate the important functions of our body and serves your overall health and well-being. In this article, we will write to you in detail about the endocannabinoid system and how it works, and what it influences.
When was this ECS discovered?
It was back in 1988, there was a study that was officially documented that had scientifically proved that every mammal has receptor sites (called neurotransmitters) that respond to the chemical compounds found in the cannabis. In 1990, another team had mapped a DNA sequence that encodes cannabinoid receptors in the brain.
This led to a G-protein-coupled receptor which was called endocannabinoids. CB1 and CB2 were those 2 receptors of ECS. CB1 is located in the brain, which signals the rest of the ECS while CB2 is present in the immune and peripheral nervous system.
Role of ECS:
This system helps to regulate various functions of our body like:
- Chronic pain
- Inflammation and other immune system responses
- Learning and memory
- Cardiovascular system functions and many more
The main reason for this ECS is that it helps maintain homeostasis despite any other external influence causing the body to get affected.
Parts of ECS:
ECS is comprised of three different parts:
- Cannabinoid receptors are present on the surface of the cells. So, when they come in contact with the phytocannabinoids (which are found in the plant) they are broken into 2 different receptors called CB1 and CB2.
- Endocannabinoids which are also called endogenous cannabinoids. These are like chemical compounds, which are found in the body that helps activate the above cannabinoids.
- Metabolic enzymes, which are protein that break down and they take up action on these endocannabinoids and phytocannabinoids once they do their work of activating these above receptors.
How does CBD affect the ECS?
CBD as compared to THC is said to have a different interaction with ECS. It does not indulge with CB1 and CB2 receptors just like THC does. Most scientists believe that ECS does not break down the ECS instead it keeps it more effective. This hemp-extracted CBD has shown interacting with numerous presynaptic receptors found in the brain. It affects the overall cannabinoids in the brain.
Just like our body goes through a deficiency of vitamins and minerals, they also have an endocannabinoid deficiency. This may lead to many problems for which more studies need to be done.
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